Dictionary > Transgenesis

Transgenesis

Definition
noun
The process of introducing transgene from one organism into another (unrelated) organism or cell
Supplement
Transgenesis refers to the process of introducing transgene (i.e. an exogenous gene) from one organism into another with the intent of enabling the latter to exhibit a new property that can be transmitted to its offspring. It can be done by the use of liposomes, plasmid vectors, viral vectors, pronuclear injection, protoplast fusion, and ballistic DNA injection.1
One of the uses of transgenesis is to transfer genes (e.g. human genes) into animals or cells to incite and observe human diseases. Animals that are used for this purpose is called transgenic animal models. Transgenic mice are one of the most common animal models used. Transgenesis is also used in order to introduce a new capability to transgenic animals, for instance, to produce therapeutic molecules.
These transgenic organisms are capable of expressing transgenes because the genetic code is fundamentally similar for all organisms. Dubbed as super mice in the 1980s, they are able to produce human protein tPA that can be used to treat blood clots.
Word origin: Latin trāns ‎(across, on the far side, beyond) + Ancient Greek génesis (origin)
See also:

Related term(s):

  • transgene
  • transgenic
  • Reference(s):

    1 Transgenesis. Retrieved from https://en.wikipedia.org/wiki/Transgenesis.


    You will also like...

    Still Water Animals
    Still Water Animals

    Animals living in aquatic habitats have diversified and evolved through time. They eventually occupy ecological niches a..

    green leaf - close up view
    Leaves

    Leaves are the major photosynthetic organ of a plant. Apart from that, they are also crucial to water movement. In this ..

    Thermographic image of face and neck
    Regulation of Organic Metabolism, Growth and Energy Balance

    The human body is capable of regulating growth and energy balance through various feedback mechanisms. Get to know the e..

    An artistic depiction of Dunkleosteus fish
    Fish

    The sea was teeming with life. Eventually, through reproduction and continued variation, fish came about. There are over..

    primitive arthropods
    Arthropods

    The arthropods were assumed to be the first taxon of species to possess jointed limbs and exoskeleton, exhibit more adva..

    Developmental Biology
    Developmental Biology

    Developmental biology is a biological science that is primarily concerned with how a living thing grows and attains matu..