Dictionary > Transgenesis

Transgenesis

Definition
noun
The process of introducing transgene from one organism into another (unrelated) organism or cell
Supplement
Transgenesis refers to the process of introducing transgene (i.e. an exogenous gene) from one organism into another with the intent of enabling the latter to exhibit a new property that can be transmitted to its offspring. It can be done by the use of liposomes, plasmid vectors, viral vectors, pronuclear injection, protoplast fusion, and ballistic DNA injection.1
One of the uses of transgenesis is to transfer genes (e.g. human genes) into animals or cells to incite and observe human diseases. Animals that are used for this purpose is called transgenic animal models. Transgenic mice are one of the most common animal models used. Transgenesis is also used in order to introduce a new capability to transgenic animals, for instance, to produce therapeutic molecules.
These transgenic organisms are capable of expressing transgenes because the genetic code is fundamentally similar for all organisms. Dubbed as super mice in the 1980s, they are able to produce human protein tPA that can be used to treat blood clots.
Word origin: Latin trāns ‎(across, on the far side, beyond) + Ancient Greek génesis (origin)
See also:

  • recombinant DNA technology

Related term(s):

  • transgene
  • transgenic
  • Reference(s):

    1 Transgenesis. Retrieved from https://en.wikipedia.org/wiki/Transgenesis.


    You will also like...

    Regulation of Biological Systems
    Regulation of Biological Systems

    Regulation of Biological Systems tutorials are focused on the modulation of biological systems from cell to population l..

    Chemical effects on plant growth and development
    Effect of Chemicals on Growth & Development in Organisms

    Plants and animals need elements, such as nitrogen, phosphorus, potassium, and magnesium for proper growth and developme..

    Genetic engineering
    Genetic Engineering Advantages & Disadvantages

    This tutorial presents the benefits and the possible adverse eventualities of genetic engineering. Know more about this ..

    Homo Species
    The Homo Species

    The evolution of the species of the genus "Homo" led to the emergence of modern humans. Find out more about human evolut..

    Freshwater Ecology
    Freshwater Ecology

    Freshwater ecology focuses on the relations of aquatic organisms to their freshwater habitats. There are two forms of co..

    Early Earth
    The Origins of Life

    This tutorial digs into the past to investigate the origins of life. The section is split into geological periods in the..

    Related Articles...

    No related articles found

    See all Related Topics