Dictionary > Corticotroph

Corticotroph

Definition
noun, plural: corticototrophs
The cell in the anterior pituitary that particularly releases adrenocorticotropic hormone (ACTH), melanocyte-stimulating hormone (MSH), and lipotropin
Supplement
The pituitary gland is the master endocrine gland of the endocrine system. It is responsible for the production and the release of different hormones that regulate various physiological processes. The pituitary gland is comprised of the anterior and the posterior pituitaries bordered by pars intermedia. The anterior pituitary is the glandular portion and release hormones that regulate growth, reproduction, lactation, and stress. There are about five types of hormone-secreting cells in the anterior pituitary classified based on the hormones that they produce and secrete: (1) somatotrophs, (2) corticotrophs, (3) thyrotrophs, (4) gonadotrophs, and (5) lactotrophs.
Corticotrophs are the cells in the anterior pituitary that release adrenocorticotropic hormone (ACTH), melanocyte-stimulating hormone (MSH), and lipotropin. They constitute about 20% of the anterior pituitary cells.
Corticotrophs release ACTH (also called corticotropin) in response to corticotropin releasing hormone (CRH) produced by the neurosecretory cells of the hypothalamus and secreted via the hypophyseal portal system. The ACTH stimulates the adrenal gland to secrete glucocorticoids, MSH, mineralocorticoid, and androgens.
Also called:

  • corticotropic cell
  • corticotrope

See also:

  • anterior pituitary
  • hormone
  • endocrine system


    You will also like...

    An artist depiction of a Precambrian multicellular life form.
    The Evolution of Cell Organelles

    The nucleus containing the genetic material, DNA, and the mitochondria, well-identified as the "powerhouse of the cell",..

    Sigmund Freud and Carl Gustav Jung
    Sigmund Freud and Carl Gustav Jung

    In this tutorial, the works of Carl Gustav Jung and Sigmund Freud are described. Both of them actively pursued the way h..

    Cambial cells
    Plant Tissues

    Plant organs are comprised of tissues working together for a common function. The different types of plant tissues are m..

    Psychiatry and mental disorders
    Psychiatry & Mental Disorders

    Different mental disorders are described here. Read this tutorial to get an overview of schizophrenia, affective mood di..

    Homeostasis by water regulation
    Homeostasis of Organism Water Regulation

    Osmoregulation is the regulation of water concentrations in the bloodstream, effectively controlling the amount of water..

    Crossing Over and Genetic Diversity
    Inheritance and Probability

    Gregor Mendel, an Austrian monk, is most famous in this field for his study of the phenotype of pea plants, including ..