(genetics) Gene knock-in, as in genetic engineering method
(chemistry) A symbol for the dissociation constant of an inhibitor
(chemistry) The measure of bond-tightness between an enzyme and a corresponding enzyme inhibitor
(chemistry) The measure of ligand binding affinity
(chemistry) Potassium iodide
In genetics and molecular biology, Ki stands for gene knock-in, or simply knock-in. A knock-in pertains to the genetic engineering method involving the insertion of a protein coding cDNA sequence at a particular locus in the chromosome of an organism, typically a laboratory mouse model.1
In chemistry, Ki is a symbol for the dissociation constant. By definition, the dissociation constant is a mathematical constant that describes the tendency of a large molecule to dissociate reversibly into smaller components. It is the equilibrium constant in a dissociation reaction. It is a type of equilibrium constant that specifically involves the measure of the propensity of dissociation of a complex molecule into its subcomponents. An example of its application is to describe how tightly a ligand binds to a particular protein. It is also referred to as the equilibrium dissociation constant or the ionization constant.

1 Gibson, Greg (2009). A Primer Of Genome Science 3rd ed. Sunderland, Massachusetts: Sinauer. pp. 301–302. ISBN 978-0-87893-236-8.

You will also like...

Control of body movement
Control of Body Movement

Some of the body movements can be controlled at will, others cannot. The body has a motor program, which is the pattern ..

Physical growth
Physical Development in Humans

This tutorial elaborates on the physical development of humans, particularly from puberty to adulthood. Read this tutori..

DNA - schematic
Genetic Mutations

This tutorial looks at the mutation at the gene level and the harm it may bring. Learn about single nucleotide polymorph..

Plant Auxins
Plant Auxins – Phototropism & Geotropism

Plants produce hormones to regulate their growth. Auxins, for instance, influence plant growth. Know the role of auxin i..

Digestion and Absorption of Food
Digestion and Absorption of Food

The gastrointestinal system breaks down particles of ingested food into molecular forms by enzymes through digestion and..

Birth Control and Contraception
Birth Control and Contraception

Different pregnancy and birth control and contraception strategies are described. Read this tutorial to learn each of th..