Definition
noun, plural: kinetochores
A protein complex that assembles at the centromeric region of the chromosome during mitosis and meiosis
Supplement
The kinetochore is a protein structure. It forms at the centromere of every chromosome. Its main function is to bind microtubules of the spindle so that during metaphase the chromosomes would be able to properly align at the metaphase plate prior to anaphase, which is the pulling of chromosomes toward opposite poles of the cell. Thus, the kinetochore is important for the proper chromosome segregation.
In most animal cells, the kinetochore is a disc-like complex forming on the side of every chromatid where spindle fibers would attach to. Thus, a human mitotic chromosome, being comprised of two sister chromatids linked together via a centromere, would have two kinetochores situated in opposite directions at the centromeric region.
The kinetochore is comprised of an inner region (called inner kinetochore) and an outer region (called outer kinetochore). The inner kinetochore is tightly bound to the centromere DNA. The outer kinetochore is the one that interacts with the microtubules. Depending on the species, the number of microtubules attached to the kinetochore varies. In humans, there are about 15 microtubules attach to the kinetochore.
Unlike the outer kinetochore that forms and becomes functional only during mitosis and meiosis, the inner kinetochore persists throughout the cell cycle.
Word origin: Greek khôros (“space”)
See also:
Dictionary > Kinetochore
You will also like...

Cell Respiration
Cell respiration is the process of creating ATP. It is "respiration" because it utilizes oxygen. Know the different stag..

Vascular Plants: Ferns and Relatives
Ferns and their relatives are vascular plants, meaning they have xylem and phloem tissues. Because of the presence of va..

Freshwater Communities & Plankton
Planktons are microscopic organisms that live suspended in aquatic habitats. There are two groups: the phytoplanktons an..

Lotic Communities & Animals
A running water environment offers numerous microhabitats for many types of animals. Similar to plants, animals in lotic..

Adaptation Tutorial
Adaptation, in biology and ecology, refers to the process or trait through which organisms or the populations in a habit..

Pollution in Freshwater Ecosystems
There are many environmental factors that arise due to the usage of water in one way or another and for every action tha..