Dictionary > Minisatellite

Minisatellite

Definition
noun, plural: minisatellites
(molecular biology) A tandem repeat ranging in length from 10 to 60 base pairs, repeated typically five to fifty times
Supplement
Tandem repeats are repeated nucleotide sequences in which the copies lie adjacent to each other. It may be repetition(s) of one or more nucleotides. For example, CG CG CG CG CG is a tandem repeat wherein the sequence CG is repeated five times. Examples of tandem repeats are satellite DNA, microsatellite, and minisatellite.
Minisatellite repeats are tandem arrays of moderately repetitive DNA sequences. The typical length is about ten to 60 base pairs repeated about five to fifty times. In humans, minisatellites are found in the telomeres and centromeres of the chromosomes. Some of them are hypermutable and as such are regarded as the most unstable region in the genome. Minisatellites are essential to understanding polymorphism and DNA fingerprinting.
The term minisatellite is sometimes used interchangeably with variable number of tandem repeat (VNTR). However, VNTR pertains not just to minisatellites but also to microsatellites. A microsatellite is similar to a minisatellite in being a stretch of DNA consisting of tandem repeats. However, a microsatellite is relatively shorter than a minisatellite.
Also called:

  • ninisatellite repeats

See also:

  • tandem repeat
  • satellite DNA
  • polymorphism
  • variable number of tandem repeat
  • telomere
  • centromere


    You will also like...

    green leaf - close up view
    Leaves

    Leaves are the major photosynthetic organ of a plant. Apart from that, they are also crucial to water movement. In this ..

    A sperm cell fertilizing an ovum
    Human Reproduction and Fertilization

    For human species to obviate extinction, reproductive mature adults should be producing viable offspring in order to con..

    Direct and indirect physiologic effects of growth hormone
    Animal Growth Hormones

    Hormones are produced in the endocrine glands of animals. The pituitary gland and hypothalamus are the most impor..

    Chemical composition of the body
    Chemical Composition of the Body

    The body is comprised of different elements with hydrogen, oxygen, carbon, and nitrogen as the major four. This tutorial..

    Homeostasis by water regulation
    Homeostasis of Organism Water Regulation

    Osmoregulation is the regulation of water concentrations in the bloodstream, effectively controlling the amount of water..

    Structural depiction of catalase, an enzyme
    Protein Activity and Cellular Metabolism

    Proteins have a crucial role in various biological activities. Get to know how proteins are able to perform as enzymes, ..