Dictionary > Myeloblast

Myeloblast

Definition
noun, plural: myeloblasts
A precursor cell that gives rise to a promyelocyte during granulopoiesis
Supplement
Hematopoiesis is the process of forming new blood cellular elements in vertebrates. It begins with a multipotent stem cell, a hemocytoblast, which gives rise to a common myeloid progenitor cell (CMP). The CMP, in turn, gives rise to granulocyte-monocyte colony forming units (CFU-GM), also called granulocyte-macrophage progenitor. The CFU-GM may partially differentiate into CFU-G (precursor in myelocyte-granulocyte series) or CFU-M (precursor in monocyte-macrophage series). The CFU-GM serves as the precursor for monoblasts and myeloblasts.
The myeloblast is a committed progenitor cell that gives rise to a promyelocyte. Its size ranges from 14 to 18 µm in diameter. It typically resides in the bone marrow. It usually has three or more nucleoli. The cytoplasm is basophilic and agranular.
The myoblasts are the first developmental stage of the myelocytic series. In this series, the developmental stages are as follows: hemocytoblast → common myeloid progenitor (or CFU-GEMM) → CFU-GM → CFU-G → myeloblast → promyelocyte → myelocyte → metamyelocyteband cellgranulocyte.
Word origin: Greek muelós (“marrow”) + Greek blastós (“germ”, “sprout”)
See also:

Related form(s):

  • myeloblastic (adjective, of, pertaining to, or relating to a myeloblast)


    You will also like...

    green plant cells
    Plant Cells vs. Animal Cells

    Plant cells have plastids essential in photosynthesis. They also have an additional layer called cell wall on their cell..

    Still Water Animals
    Still Water Animals

    Animals living in aquatic habitats have diversified and evolved through time. They eventually occupy ecological niches a..

    Gene Pool and Speciation
    The Gene Pool and Population Genetics

    According to Charles Darwin's theory of natural selection, preferable genes are favored by nature in the gene pool, and ..

    bryophyte - sporophyte and gametophyte
    Meiosis and Alternation of Generations

    Plants are characterized by having alternation of generations in their life cycles. This tutorial is a review of plant m..

    Sigmund Freud and Carl Gustav Jung
    Sigmund Freud and Carl Gustav Jung

    In this tutorial, the works of Carl Gustav Jung and Sigmund Freud are described. Both of them actively pursued the way h..

    sponge
    Primitive Animals

    Life, as we know it today, is presumed to have started in the sea and many of them were likely eukaryotic animal-like or..