Dictionary > Ribozyme

Ribozyme

Definition
noun, plural: ribozymes
RNA molecule that acts as an enzyme in the aminotransferase activity of the ribosome and in the cleavage of its own or another RNA
Supplement
Ribozymes are RNA enzymes that catalyze certain biochemical reactions, such as in the aminotransferase activity of the ribosome and in the cleavage (or ligation) of its own or another RNA. They are also observed to participate in viral replication.
Ribozyme occurs within the ribosome. Ribosomes are biomolecules in the cytoplasm that participate in protein synthesis. Ribosomal RNAs form the two subunits of ribosome, particularly the large subunit and the small subunit. It is the large subunit of the ribosome that acts as ribozyme, catalyzing peptide bond formation between two amino acids.
The discovery of ribozyme in 1982 led to the thought that RNA can be a genetic material as well as a biological catalyst, and therefore, contributed to the RNA world hypothesis. This hypothesis proposed that RNA might have been essential in the evolution of prebiotic self-replicating systems. The study of ribozymes is referred to as ribozymology.
Examples of ribozymes are hammerhead ribozyme, hairpin ribozyme, and leadzyme.
Also called:

  • RNAzyme
  • ribonucleic acid enzyme
  • RNA enzyme

See also:

  • ribosome
  • ribosomal RNA
  • ribonucleic acid
  • Related term(s):


    You will also like...

    Birth Control and Contraception
    Birth Control and Contraception

    Different pregnancy and birth control and contraception strategies are described. Read this tutorial to learn each of th..

    Freshwater lake ecosystem
    Freshwater Producers and Consumers

    Freshwater ecosystem is comprised of four major constituents, namely elements and compounds, plants, consumers, and deco..

    Gene Regulation in Eukaryotes
    Gene Regulation in Eukaryotes

    This tutorial is about genetic regulation in eukaryotes. Learn about the general structure of a eukaryotic gene, the tra..

    complete-dominance
    Dominance

    This tutorial presents Gregor Mendel's law of dominance. Learn more about this form of inheritance and how it can be pre..

    DNA molecule
    Genetic Control – On and Off Genes

    Genes are the blueprint of our bodies, a blueprint that creates a variety of proteins essential to any organism's surviv..

    Direct and indirect physiologic effects of growth hormone
    Animal Growth Hormones

    Hormones are produced in the endocrine glands of animals. The pituitary gland and hypothalamus are the most impor..