Dictionary > Small-scale mutation

Small-scale mutation

Definition
noun, plural: small-scale mutations
(genetics) A type of mutation characterized by a change of one or few nucleotides of a gene
Supplement
Mutation is a change in the nucleotide sequence of a gene or a chromosome. It may be classified into various ways. One of these classifications involves classifying mutations based on the effect of mutation on the gene structure: (1) small-scale mutations and (2) large scale mutations.
Small-scale mutations are a type of mutation where one or few nucleotides of a gene are affected. These are further classified into substitution mutations, insertions, and deletions. Substitution mutations are a type of mutation in which a single nucleotide is substituted with a different nucleotide. They are further typified into silent mutations, missense mutations, and nonsense mutations). Insertion mutations are mutations caused by the addition of one or more extra nucleotides into the DNA. Deletion mutations are a type of mutation wherein one or more nucleotides are removed from the DNA. When there is only one nucleotide involved in substitution insertion, and deletion, it is particularly referred to as a point mutation.
Small-scale mutations may result in an altered sequence of amino acid during translation. One possible outcome of such mutation is to render the newly synthesized protein ineffective.
Compare:

  • large-scale mutation

See also:

  • mutagenesis
  • mutation
  • DNA
  • substitution mutation
  • insertion mutation
  • deletion mutation


  • You will also like...

    Birth of a Human Baby
    Birth of a Human Baby

    Following nine months inside the mother's womb is the birth of the baby. Know the different stages of the birthing proce..

    Homo Species
    The Homo Species

    The evolution of the species of the genus "Homo" led to the emergence of modern humans. Find out more about human evolut..

    Salmon jumping upstream in the river
    Lotic Communities & Animals

    A running water environment offers numerous microhabitats for many types of animals. Similar to plants, animals in lotic..

    Control of body movement
    Control of Body Movement

    Some of the body movements can be controlled at will, others cannot. The body has a motor program, which is the pattern ..

    Circulation
    Circulation

    The circulatory system is key to the transport of vital biomolecules and nutrients throughout the body. Learn about the ..

    bryophyte - sporophyte and gametophyte
    Meiosis and Alternation of Generations

    Plants are characterized by having alternation of generations in their life cycles. This tutorial is a review of plant m..