A form of dense connective tissue in which the extracellular fibers (in particular, collagen fibers) are not arranged in parallel bundles (as in the dense regular connective tissue)
The dense connective tissue is a type of connective tissue proper that consists predominantly of fibers, especially type I collagen. The fibroblasts in the matrix generate these fibers. As the name implies, this type of connective tissue proper is dense or closely compacted in contrast to the other type, which is the loose connective tissue. Two forms of dense connective tissues include (1) dense regular connective tissue and (2) dense irregular connective tissue.
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In dense irregular connective tissue, the collagen fibers are not arranged in parallel bundles as opposed to dense regular connective tissue. Nevertheless, both the regular and irregular forms of dense connective tissues are comprised chiefly of collagen fibers. Both of them have higher proportions of collagen fiber than cell elements and ground substance. The predominant cell type is fibroblast, the cell type that synthesizes extracellular fibers, especially collagen.
The dense irregular connective tissues are found in the lower layers of the skin (dermis) and in the protective white layer of the eyeball.