Dictionary > Lyase

Lyase

Definition
noun, plural: lyases
(biochemistry) An enzyme that catalyzes the breaking of a chemical bond through means not involving hydrolysis or oxidation, and forms a double bond or adds a group to a double bond
Supplement
An enzyme is a catalyst or a chemical produced by cells to speed up a biochemical reaction. It is usually a protein molecule with a characteristic sequence of amino acids that fold to produce a specific three-dimensional structure, which gives the molecule unique properties. Other molecule with catalytic activity is ribozyme, an enzyme made of RNA rather than protein. Enzymes may be classified and named according to the reaction they catalyze: (1) oxidoreductases, (2) transferases, (3) lyases, (4) isomerases, and (6) ligases.
Lyases are enzymes that catalyze the breaking a chemical bond between two parts of a molecule through biochemical means other than hydrolysis and oxidation. They often form a double bond or add a new ring structure. An example is the lyase that acts on ATP resulting in the formation of cAMP and PPi.
One of the distinctive characteristics of a lyase is requiring one substrate for the reaction in one direction and two substrates for the reverse reaction (referred to as Michael addition).
Lyases include decarboxylases, aldolases and dehydratases.
Compare:

  • synthase

See also:

  • enzyme
  • Related term(s):

    • Atp citrate lyase
    • Atp citrate pro-3s-lyase
    • Cystathionine gamma-lyase
    • Diaminopropionate ammonia-lyase
    • Formate hydrogen lyase
    • L-cysteine-cystine c-s lyase
    • L-methionine gamma-lyase
    • O-acetylhomoserine thiol-lyase
    • Protein a24 lyase
    • Spore photoproduct lyase
    • Threonine acetaldehyde-lyase


    You will also like...

    Oligodendrocyte and Schwann cell
    The Central Nervous System

    Myelin sheath is essential for a faster conductivity of signals. Know more about this feature of some neurons in the Cen..

    Neurology of Illusions
    Neurology of Illusions

    Illusions are the perceptions and sensory data obtained from situations in which human error prevents us from seeing the..

    Biosecurity and Biocontrol
    Biosecurity and Biocontrol

    This lesson explores the impact of biosecurity threats, and why they need to be identified and managed. Examples to incl..

    Cell Respiration
    Cell Respiration

    Cell respiration is the process of creating ATP. It is "respiration" because it utilizes oxygen. Know the different stag..

    human brain structure
    The Conscious & Unconscious Nervous System

    This tutorial elaborates on how the nervous system works, particularly at the tissue level of the brain. There are three..

    temperature - abiotic factor
    Abiotic and Biotic Factors

    This tutorial deals with the abiotic factors of the freshwater environment that determine what sort of life would be sui..

    Related Articles...

    No related articles found

    See all Related Topics