Dictionary > Monosomy


(genetics) A type of aneuploidy characterized by the loss of a single chromosome of the normal complement
Aneuploidy is a chromosomal variation due to a loss or a gain of one or more chromosomes resulting in the deviation from the normal or the usual number of chromosomes. The different conditions of aneuploidy are nullisomy (2N-2), monosomy (2N-1), trisomy (2N+1), and tetrasomy (2N+2).
Monosomy is a type of aneuploidy where there is a loss of a single chromosome of the normal complement. The chromosomal composition is represented by 2N-1. A cell or an organism exhibiting monosomy is referred to as monosomic. Monosomy may be caused by a nondisjunction during cell division, particularly meiosis. A partial monosomy can occur when only a portion of the chromosome is lost and therefore there is only a single copy of the chromosome while the rest has two copies. Examples of monosomy in humans are Turner syndrome (usually with one X chromosome only and the other is missing), cri du chat syndrome (where the end of the short p arm of chromosome 5 is missing), and 1p36 deletion syndrome (where the end of the short p arm of chromosome 1 is missing).
See also:

Related form(s):

  • monosomic (adjective, of, relating to, or characterized by, monosomy; noun, a cell or an organism in monosomy and a chromosomal composition designated as 2N-1)

    You will also like...

    Balanced Diet
    A Balanced Diet – Minerals and Proteins

    Proteins and minerals can be derived from various dietary sources. They are essential for the proper growth and developm..

    Population Growth and Survivorship
    Population Growth and Survivorship

    This lesson looks at population attributes, regulation, and growth. It also covers population genetics, particularly gen..

    Freshwater Ecology
    Freshwater Ecology

    Freshwater ecology focuses on the relations of aquatic organisms to their freshwater habitats. There are two forms of co..

    human respiratory system

    The human respiratory system is an efficient system of inspiring and expiring respiratory gases. This tutorial provides ..

    Early Earth
    The Origins of Life

    This tutorial digs into the past to investigate the origins of life. The section is split into geological periods in the..

    Lotic community of algal species
    Lotic Communities & Algae

    Lotic communities have conditions that are rather harsh for typical plants. Thus, the diversity of plant species in loti..