Dictionary > Paracentric inversion

Paracentric inversion

Definition
noun, plural: paracentric inversions
(genetics) An inversion of a segment of chromosome in which the centromere is not included, and both breaks occur in the single arm of a chromosome
Supplement
Chromosomal inversion is a type of a large-scale mutation since it involves several nucleotides of a gene within a large chromosomal region. It can be detected through genetic analysis and cytogenetic techniques. It is characterized by a rearrangement within the chromosome. It results from a double break in a segment of the chromosome, with end for end rotation of the fragment between the fracture lines, and re-fusion of the fragments. This results in the reversal of the order of genes in that segment. There are of two types of chromosomal inversions: pericentric inversion and paracentric inversion. A pericentric inversion is a chromosomal inversion that includes the centromere whereas a paracentric inversion is one that does not include the centromere. Furthermore, in pericentric inversion, the break point occurs in each arm. In paracentric inversion, both breaks occur in one arm of the chromosome.
Inversions may not cause abnormalities in carriers as long as there is no extra or missing genetic information. However, individuals who are heterozygous for an inversion, there is a rise in the production of abnormal chromatids, especially when crossing-over occurs within the span of the inversion.
Word origin: Greek para- (“beside, near, from, against, contrary to”) + centric (center)
Compare:

See also:

  • chromosomal inversion
  • chromosome
  • mutation
  • centromere


  • You will also like...

    Selective Breeding
    Selective Breeding

    Gregor Mendel's studies into Monohybrid and Dihybrid crossing and Charles Darwin's study of evolution and natural select..

    Electromagnetic spectrum of a brain
    Sleep and Dreams – Neurology

    While learning and intelligence are associated with the functions of a conscious mind, sleep and dreams are activities o..

    Chemical effects on plant growth and development
    Effect of Chemicals on Growth & Development in Organisms

    Plants and animals need elements, such as nitrogen, phosphorus, potassium, and magnesium for proper growth and developme..

    Psychiatry and mental disorders
    Psychiatry & Mental Disorders

    Different mental disorders are described here. Read this tutorial to get an overview of schizophrenia, affective mood di..

    complete-dominance
    Dominance

    This tutorial presents Gregor Mendel's law of dominance. Learn more about this form of inheritance and how it can be pre..

    Thermographic image of face and neck
    Regulation of Organic Metabolism, Growth and Energy Balance

    The human body is capable of regulating growth and energy balance through various feedback mechanisms. Get to know the e..

    Related Articles...

    No related articles found

    See all Related Topics