Dictionary > Paracentric inversion

Paracentric inversion

Definition
noun, plural: paracentric inversions
(genetics) An inversion of a segment of chromosome in which the centromere is not included, and both breaks occur in the single arm of a chromosome
Supplement
Chromosomal inversion is a type of a large-scale mutation since it involves several nucleotides of a gene within a large chromosomal region. It can be detected through genetic analysis and cytogenetic techniques. It is characterized by a rearrangement within the chromosome. It results from a double break in a segment of the chromosome, with end for end rotation of the fragment between the fracture lines, and re-fusion of the fragments. This results in the reversal of the order of genes in that segment. There are of two types of chromosomal inversions: pericentric inversion and paracentric inversion. A pericentric inversion is a chromosomal inversion that includes the centromere whereas a paracentric inversion is one that does not include the centromere. Furthermore, in pericentric inversion, the break point occurs in each arm. In paracentric inversion, both breaks occur in one arm of the chromosome.
Inversions may not cause abnormalities in carriers as long as there is no extra or missing genetic information. However, individuals who are heterozygous for an inversion, there is a rise in the production of abnormal chromatids, especially when crossing-over occurs within the span of the inversion.
Word origin: Greek para- (“beside, near, from, against, contrary to”) + centric (center)
Compare:

See also:

  • chromosomal inversion
  • chromosome
  • mutation
  • centromere


    You will also like...

    Growth Patterns
    Growth Patterns

    This tutorial describes the sigmoid curve, annual plant growth, tree growth, human growth, and insect growth as the grow..

    river
    Running Water Freshwater Communities

    This tutorial introduces flowing water communities, which bring new and dithering factors into the equation for possible..

    "Opabinia regalis"
    The Evolutionary Development of Multicellular Organisms

    Multicellular organisms evolved. The first ones were likely in the form of sponges. Multicellularity led to the evolutio..

    Mātauranga Māori and Science Collaboration
    Mātauranga Māori and Science

    Mātauranga Māori is the living knowledge system of the indigenous people of New Zealand, including the relationships t..

    Body temperature regulation by the hypothalamus
    Temperature Regulation in Animals

    This tutorial elucidates body temperature regulation. Know the details here to learn how the body sets the body temperat..

    Sigmund Freud and Carl Gustav Jung
    Sigmund Freud and Carl Gustav Jung

    In this tutorial, the works of Carl Gustav Jung and Sigmund Freud are described. Both of them actively pursued the way h..