Dictionary > Paracentric inversion

Paracentric inversion

Definition
noun, plural: paracentric inversions
(genetics) An inversion of a segment of chromosome in which the centromere is not included, and both breaks occur in the single arm of a chromosome
Supplement
Chromosomal inversion is a type of a large-scale mutation since it involves several nucleotides of a gene within a large chromosomal region. It can be detected through genetic analysis and cytogenetic techniques. It is characterized by a rearrangement within the chromosome. It results from a double break in a segment of the chromosome, with end for end rotation of the fragment between the fracture lines, and re-fusion of the fragments. This results in the reversal of the order of genes in that segment. There are of two types of chromosomal inversions: pericentric inversion and paracentric inversion. A pericentric inversion is a chromosomal inversion that includes the centromere whereas a paracentric inversion is one that does not include the centromere. Furthermore, in pericentric inversion, the break point occurs in each arm. In paracentric inversion, both breaks occur in one arm of the chromosome.
Inversions may not cause abnormalities in carriers as long as there is no extra or missing genetic information. However, individuals who are heterozygous for an inversion, there is a rise in the production of abnormal chromatids, especially when crossing-over occurs within the span of the inversion.
Word origin: Greek para- (“beside, near, from, against, contrary to”) + centric (center)
Compare:

See also:

  • chromosomal inversion
  • chromosome
  • mutation
  • centromere


    You will also like...

    dinosaurs
    The Dinosaurs

    Dinosaurs represented a major turn in the evolutionary development of organisms on Earth. The first dinosaurs were presu..

    human respiratory system
    Respiration

    The human respiratory system is an efficient system of inspiring and expiring respiratory gases. This tutorial provides ..

    Biological Cell schematic diagram
    Biological Cell Introduction

    It only takes one biological cell to create an organism. A single cell is able to keep itself functional through its 'mi..

    Transpiration
    Water in Plants

    The movement of molecules (specifically, water and solutes) is vital to the understanding of plant processes. This tuto..

    An artist's depiction of the origin of amphibians
    Amphibians & Early Reptiles

    Obtaining air outside an aquatic environment required species to acquire suitable adaptations, and this was the case of ..

    Sensory systems
    Sensory Systems

    A sensory system is a part of the nervous system consisting of sensory receptors that receive stimuli from the internal ..