31 results found

Search Results for: ligand

Ligand gated ion channels

Ligand gated ion channel a transmembrane ion channel whose permeability is increased by the binding of a specific ligand,... Read More

Ligand

Definition noun, plural: ligands (1) A molecule, ion or atom bonded to the central metal atom of a coordination... Read More

Protein Activity and Cellular Metabolism

Protein Binding Sites The ability of various molecules and ions to bind to specific sites on the protein surface forms the... Read More

Monod-Wyman-Changeux model

Definition noun (biochemistry) A model used to describe the allosteric forms of cooperativity Supplement The... Read More

Affinity chromatography

Affinity chromatography (Science: investigation) a technique of analytical chemistry used to separate and purify a... Read More

Ki

Definition (genetics) Gene knock-in, as in genetic engineering method (chemistry) A symbol for the dissociation constant of... Read More

Saturation of receptors

saturation of receptors saturation, the state in which all receptors are effectively occupied all the time, can be said to... Read More

Gated ion channel

(Science: physiology) transmembrane proteins of excitable cells, that allow a flux of ions to pass only under defined... Read More

Chelating agent

Definition noun, plural: chelating agents A ligand, often an organic compound, which reacts with a metal ion to produce a... Read More

Down-regulation

Down-regulation (Science: physiology) development of a refractory or tolerant state consequent upon repeated administration... Read More

Phosphorylation

Phosphorylation Definition We can define phosphorylation as a biochemical process in which a phosphate molecule is added to... Read More

Glycosaminoglycan

Definition noun (biochemistry) The polysaccharide unit of proteoglycan Supplement Glycosaminoglycans are the polysaccharide... Read More

Beta barrel

Definition noun, plural: beta barrels A large β-sheet that twists and coils to form a closed structure where the first... Read More

KD

Definition noun (biochemistry) An equilibrium constant for dissociation (biochemistry) An abbreviation for kilodalton, also... Read More

Movement of Molecules Across Cell Membranes

Diffusion Diffusion is essentially the movement of molecules from a region of higher concentration to a region of lower... Read More

Extrinsic pathway

Definition noun (1) (hematology) One of the two initial pathways for the conversion of the prothrombin to thrombin in the... Read More

Gynaecophore

Definition noun, plural: gynecophores A receptacle, often in the ventral body, of certain adult male animals (dioecious... Read More

Affinity

Definition noun, plural: affinities (1) (taxonomy) The resemblances in structure between two organisms or between biological... Read More

Sorting out

sorting out phenomenon observed to occur when mixed aggregates of dissimilar embryonic cell types are formed in vitro. The... Read More

Adenosine

Definition noun plural: adenosines a·den·o·sine, əˈdɛn əˌsin A purine nucleoside that has adenine bound to a... Read More

Up-regulation physiology

up-regulation (physiology) process that increases ligand/receptor interactions due to an increase in the number of available... Read More

Modulation

modulation --> neuromodulation alteration in the effectiveness of voltage gated or ligand gated ion channels by changing... Read More

Active centre

Active centre The part of a macromolecule at which a substrate or ligand, upon binding, produces biological activity; for an... Read More

Dissociation constant

Definition noun (1) A mathematical constant that describes the tendency of a large molecule to dissociate reversibly into... Read More

Adair-koshland-nemethy-filmer model

Adair-koshland-nemethy-filmer model --> Koshland-Nemethy-Filmer model (Science: biochemistry, chemistry) a model to... Read More

Competitive binding assay

Definition An assay based on the competition between labeled and unlabeled ligand for the reactive sites of a particular... Read More

Cofactor

Definition noun, plural: cofactors (biochemistry) An inorganic complement of an enzyme reaction Supplement Cofactors... Read More

Hill coefficient

Hill coefficient a measure of cooperativity in a binding process. a hill coefficient of 1 indicates independent binding, a... Read More

Cognate

Cognate (Science: biochemistry) refers to two biomolecules that typically interact (for example, a receptor and its... Read More

Effector

Definition noun, plural: effectors (biochemistry) A molecule that binds to a protein and affects the function of that... Read More

Conformational change

Conformational change (Science: cell biology) alteration in the shape usually the tertiary structure of a protein as a... Read More